Alexa Fluor 488 anti-mouse CD68 Antibody anti-CD68 - FA-11,BioLegend,137011

Additional reported (for relevant formats) applications include: immunoprecipitation1, 2, Western Blot1, 2, immunohistochemical staining of frozen sections2and paraformaldehyde-fixed paraffin-embedded sections3, and spatial biology (IBEX)9,10.

Host

Rat

Reactivity

Mouse

Application

ICFC - Quality testedFC, 3D IHC - Verified

Platform ID

BAB847417626

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Contact

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Product Specifications
Scientific Background

Specifications

NameAlexa Fluor 488 anti-mouse CD68 Antibody anti-CD68 - FA-11
Cat. No.137011
HostRat
RRIDAB_2074847 (BioLegend Cat. No. 137011)AB_2074846 (BioLegend Cat. No. 137012)
IsotypeRat IgG2a
ReactivityMouse
ApplicationICFC - Quality testedFC, 3D IHC - Verified
ClonalityMonoclonal
Clone NumberFA-11
Concentration0.5 mg/ml
TargetCD68
ImmunogenPurified Con A receptor glycoproteins from the P815 cell line
PurityThe antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

Mouse CD68, also known as macrosialin, is an 85-115 kD member of the lysosomal-associated membrane protein (LAMP) family. It is a heavily glycosylated and predominantly intracellular protein, mainly in late endosomes. Macrosialin is the murine homolog to the human macrophage glycoprotein CD68. It is expressed on tissue macrophages, Langerhans cells and at low levels on dendritic cells. Lamp proteins may have functions relating to cell-cell interaction or cell-ligand interaction. The biological function of CD68 is not completely understood.

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