Alexa Fluor® 488 anti-mouse CD74 (CLIP) Antibody anti-CD74 (CLIP) - In1/CD74,BioLegend,151006

This clone is also known as In1 and In-1. Additional reported applications (for the relevant formats) include: immunohistochemistry1, immunoprecipitation3, and western blotting4.

Host

Rat

Reactivity

Mouse

Application

FC -Quality testedIHC-F -Verified

Platform ID

BAB489022152

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NameAlexa Fluor® 488 anti-mouse CD74 (CLIP) Antibody anti-CD74 (CLIP) - In1/CD74
Cat. No.151006
HostRat
RRIDAB_2750325 (BioLegend Cat. No. 151005)AB_2750326 (BioLegend Cat. No. 151006)
IsotypeRat IgG2b, κ
ReactivityMouse
ApplicationFC -Quality testedIHC-F -Verified
ClonalityMonoclonal
Clone NumberIn1/CD74
Concentration0.5 mg/ml
TargetCD74
PurityThe antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD74, also known as CLIP, is a 33.5kD homotrimer and functions as a MHC class II chaperone for exogenous peptides and other MHC class II molecules. CD74 binds MIF and regulates innate and adaptive immunity through CD44 signaling. It is found primarily on B-cells, monocytes, macrophages and dendritic cells, but can also be found on activated T-cells, endothelial and epithelial cells.

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