Alexa Fluor 488 anti-mouse CD83 Antibody anti-CD83 - Michel-19,BioLegend,121512

Additional reported applications (for relevant formats of this clone) include: immunohistochemistry of acetone - fixed frozen sections4.

Host

Rat

Reactivity

Mouse

Application

FC - Quality tested

Platform ID

BAB629177374

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NameAlexa Fluor 488 anti-mouse CD83 Antibody anti-CD83 - Michel-19
Cat. No.121512
HostRat
RRIDAB_2074747 (BioLegend Cat. No. 121511)AB_2244430 (BioLegend Cat. No. 121512)
IsotypeRat IgG1, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberMichel-19
Concentration0.5 mg/ml
TargetCD83
ImmunogenRecombinant mouse CD83 protein
PurityThe antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD83 is a 45 kD type I transmembrane protein. It belongs to immunoglobulin superfamily and is expressed on mature dendritic cells and activated lymphocytes. CD83 is involved in the regulation of T cell development and immune response. Soluble form CD83 has been reported to inhibit dendritic cell maturation and dendritic cell-mediated T cell proliferation. Murine CD83 ligand has been found on B cells.

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