Alexa Fluor 488 anti-mouse I-Ad Antibody anti-I-Ad - 39-10-8,BioLegend,115008
Additional reported applications (for the relevant formats) include: immunofluorescence microscopy2, and immunohistochemical staining of acetone-fixed frozen sections.Does not cross-react with other haplotypes (e.g.,a, b, k, p, q, s).
Host
Mouse
Reactivity
Mouse
Application
FC -Quality tested
Platform ID
BAB618893577
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameAlexa Fluor 488 anti-mouse I-Ad Antibody anti-I-Ad - 39-10-8
Cat. No.115008
HostMouse
RRIDAB_493147 (BioLegend Cat. No. 115008)
IsotypeMouse (C3H.SW) IgG3, κ
ReactivityMouse
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone Number14526
Concentration0.5 mg/ml
TargetI-Ad
Immunogen(C3H x BALB/c)F1mouse cells
PurityThe antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
The 39-10-8 antibody reacts with the I-AdMHC class II alloantigen. These class II molecules are expressed on antigen presenting cells (including B cells) and a subset of T cells from H-2dbearing mice and are involved in antigen presentation to T cells expressing CD3/TCR and CD4 proteins. The 39-10-8 antibody does not cross-react with other haplotypes (a, b, k, p, q, s), but has been demonstrated to cross-react with the g7 haplotype.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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