Alexa Fluor 488 anti-mouse/human GL7 Antigen T and B cell Activation Marker Antibody anti-GL7 - GL7,BioLegend,144612
The GL7 antibody does not block the binding of CD22 with sulfated a2-6-sialyl-LacNAc.Cross-reactivity to ferret has been reported by a collaborator, but not verified in house.
Host
Rat
Reactivity
Mouse, Human
Application
FC -Quality testedIHC-F -Verified
Platform ID
BAB538409699
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
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Product Specifications
Scientific Background
Specifications
NameAlexa Fluor 488 anti-mouse/human GL7 Antigen T and B cell Activation Marker Antibody anti-GL7 - GL7
Cat. No.144612
HostRat
RRIDAB_2563284 (BioLegend Cat. No. 144611)AB_2563285 (BioLegend Cat. No. 144612)
IsotypeRat IgM, κ
ReactivityMouse, Human
ApplicationFC -Quality testedIHC-F -Verified
ClonalityMonoclonal
Clone NumberGL7
Concentration0.5 mg/ml
ImmunogenLPS activated DBA/J mouse B cells
PurityThe antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
The GL7 antigen, also known as Ly77, is a 35 kD protein. The GL7 antigen has an epitope containing non-sulfated α2-6-sialyl-LacNAc recognized by the GL7 antibody. The GL7 antigen is expressed by pre-B and immature B cells, activated T and B cells, and about 20% of TCR-bright thymocytes. It is upregulated on mouse splenocytes following activation. It may play a role in regulation or adhesion. GL7 high-expressing B cells show higher antibody production and antigen presenting capacity.
Category Paths
- Products>Primary Antibodies>IHC Antibodies
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