Alexa Fluor 488 anti-rat CD45RA Antibody anti-CD45RA - OX-33,BioLegend,202310

Additional reported applications (for the relevant formats) include: immunohistochemistry of acetone-fixed frozen sections1.

Host

Mouse

Reactivity

Rat

Application

FC -Quality tested

Platform ID

BAB325266999

BioLegend

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Contact

Tel: 1-858-455-9588
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Product Specifications
Scientific Background

Specifications

NameAlexa Fluor 488 anti-rat CD45RA Antibody anti-CD45RA - OX-33
Cat. No.202310
HostMouse
RRIDAB_572043 (BioLegend Cat. No. 202310)
IsotypeMouse IgG1, κ
ReactivityRat
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone NumberOX-33
Concentration0.5 mg/ml
TargetCD45RA
ImmunogenLeukocyte common antigen purified from rat splenocytes.
PurityThe antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD45 is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets. CD45RA is one of the CD45 isoforms with a molecular weight of 200-220 kD. It is expressed almost exclusively on B cells. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins, including galectin-1, CD2, CD3, and CD4.

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