Alexa Fluor 594 anti-PodoplaninLymphatic Endothelial Marker Antibody, Podoplanin, D2-40,BioLegend,916607

Additional reported applications (for the relevant formats) include: ELISA Detection5and immunocytochemistry4.

Host

Mouse

Reactivity

Human

Application

IHC-P -Quality tested

Platform ID

BAB154826321

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NameAlexa Fluor 594 anti-PodoplaninLymphatic Endothelial Marker Antibody, Podoplanin, D2-40
Cat. No.916607
HostMouse
RRIDAB_2801252 (BioLegend Cat. No. 916607)AB_2801253 (BioLegend Cat. No. 916608)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationIHC-P -Quality tested
ClonalityMonoclonal
Clone NumberD2-40
Concentration0.5 mg/ml
TargetPodoplanin
ImmunogenM2A protein derived from human germ cell tumors.
PurityThe antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 594 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

Podoplanin is expressed by a variety of normal cells, which include breast and prostate myopepithelial cells, follicular dendritic cells, basal keratinocytes of the skin and cervix (focal), type I pneumocytes, ependymal cells, and fetal cerebral germinal matrix cells. Podoplanin is a marker of lymphatic differentiation because it is expressed by normal human lymphatic endothelium, but not by vascular endothelium. It is diagnostically a useful marker for the evaluation of a variety of neoplasms, including Kaposi sarcoma mesothelioma, testicular germ cell tumors, and cutanneous sebaceous neoplasms.

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