Alexa Fluor 594 anti-human CD107b LAMP-2 Antibody anti-CD107b - H4B4,BioLegend,354309
Additional reported applications (for the relevant formats) include: immunohistochemical staining of frozen glomeruli2and immunofluorescent staining of neutrophils2,3.This antibody is specific to human LAMP-2. Positive control: Hela cells; LAMP-2 molecular weight appears to be at ~110 kDa on the gel due to high glycosylation.
Host
Mouse
Reactivity
Human
Application
IHC-P -Quality tested
Platform ID
BAB102540166
BioLegend
Contact
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Product Specifications
Scientific Background
Specifications
NameAlexa Fluor 594 anti-human CD107b LAMP-2 Antibody anti-CD107b - H4B4
Cat. No.354309
HostMouse
RRIDAB_2721377 (BioLegend Cat. No. 354309)AB_2721378 (BioLegend Cat. No. 354310)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationIHC-P -Quality tested
ClonalityMonoclonal
Clone NumberH4B4
Concentration0.5 mg/ml
TargetCD107b
ImmunogenAdult human adherent spleen cells
PurityThe antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 594 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD107b, also known as LAMP-2, is a 105 kD, highly gylcosylated, type I transmembrane protein. CD107b is expressed in lysosomal/endosomal membranes in nearly all cells, and on the surface of activated platelets, activated lymphocytes and some tumor cell lines. LAMP-2 is known to have roles in cell adhesion and cellular homeostasis, including autophagocytosis and antigen presentation.
Category Paths
- Products>Primary Antibodies>IHC Antibodies
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