Alexa Fluor 594 anti-human Perforin Antibody anti-Perforin - dG9,BioLegend,308124
Clone dG9 primarily recognizes perforin associated with cytotoxic granules9. Additional reported applications (for the relevant formats) include: immunoprecipitation, intracellular flow cytometric analysis and immunofluorescence microscopy5,7, and immunohistochemical staining of acetone-fixed frozen tissue sections and formalin-fixed paraffin-embedded tissue sections1,4.Does not cross-react with mouse1.
Host
Mouse
Reactivity
Human
Application
ICC - Quality tested
Platform ID
BAB030763371
BioLegend
Contact
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Product Specifications
Scientific Background
Specifications
NameAlexa Fluor 594 anti-human Perforin Antibody anti-Perforin - dG9
Cat. No.308124
HostMouse
RRIDAB_2566802 (BioLegend Cat. No. 308124)
IsotypeMouse IgG2b, κ
ReactivityHuman
ApplicationICC - Quality tested
ClonalityMonoclonal
Clone NumberdG9
Concentration0.5 mg/mL
TargetPerforin
ImmunogenPurified granules from the human lymphoma cell line
PurityThe antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 594 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
Perforin is a 70 kD cytolytic protein that is expressed in the cytoplasmic granules of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells. Perforin is one of the major effector molecules used by cytotoxic T cells and NK cells to mediate targeted cell lysis.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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