Alexa Fluor 594 anti-mouse CD326 Ep-CAM Antibody anti-CD326 - G8.8,BioLegend,118222

Additional reported applications for clone G8.8 (for the relevant formats) include: immunohistochemistry of frozen sections: acetone fixed1, with or without OCT embedding2,4, and spatial biology (IBEX)13,14.

Host

Rat

Reactivity

Mouse

Application

ICC -Quality testedIHC-F, 3D IHC -VerifiedSB -Reported in the literature, not verified in house

Platform ID

BAB224004364

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NameAlexa Fluor 594 anti-mouse CD326 Ep-CAM Antibody anti-CD326 - G8.8
Cat. No.118222
HostRat
RRIDAB_2563322 (BioLegend Cat. No. 118222)
IsotypeRat IgG2a, κ
ReactivityMouse
ApplicationICC -Quality testedIHC-F, 3D IHC -VerifiedSB -Reported in the literature, not verified in house
ClonalityMonoclonal
Clone NumberG8.8
Concentration0.5 mg/mL
TargetCD326
ImmunogenTE-71 thymic epithelial cell line
PurityThe antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 594 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

EpCAM (CD326) mediates calcium-independent homophilic cell to cell adhesion. It may also function as a growth factor receptor. It is thought to be involved in maintaining cells in position during proliferation. Expression of EpCAM seems to correlate inversely with the level of E-cadherin (CD324). EpCAM is considered important in tumor biology.

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