Alexa Fluor 594 anti-mousehuman Ki-67 Antibody anti-KI-67 - 11F6,BioLegend,151213
Host
Rat
Reactivity
Mouse, Human
Application
IHC-F -Quality tested
Platform ID
BAB854403007
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
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Product Specifications
Scientific Background
Specifications
NameAlexa Fluor 594 anti-mousehuman Ki-67 Antibody anti-KI-67 - 11F6
Cat. No.151213
HostRat
RRIDAB_2721388 (BioLegend Cat. No. 151213)AB_2721389 (BioLegend Cat. No. 151214)
IsotypeRat IgG2b, κ
ReactivityMouse, Human
ApplicationIHC-F -Quality tested
ClonalityMonoclonal
Clone Number11F6
Concentration0.5 mg/ml
TargetKi-67
ImmunogenE. coliexpressed, N-terminal His-Thioredoxin-tagged, partial mKi-67 (1816-2163 aa) recombinant protein.
PurityThe antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 594 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
The nuclear protein Ki-67 was first identified by the monoclonal antibody Ki-67, which was generated by immunizing mice with nuclei of the L428 Hodgkin lymphoma cell line. Ki-67 protein plays an essential role in ribosomal RNA transcription and cell proliferation. Expression of Ki-67 occurs during G1, S, G2, and M phase. While in G0 phase, the Ki-67 protein is not detectable. Ki-67 is strongly expressed in proliferating cells and has been reported as a prognostic marker in various tumors.
Category Paths
- Products>Primary Antibodies>IHC Antibodies
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