Alexa Fluor® 647 Anti-PD-L2 antibody [24F.10C12],Abcam,AB243086

Host

Mouse

Reactivity

Human

Application

Flow Cyt

Conjugate

Alexa Fluor® 647

Platform ID

BAB752484365

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAlexa Fluor® 647 Anti-PD-L2 antibody [24F.10C12]
Cat. No.AB243086
HostMouse
IsotypeIgG2a
ReactivityHuman
ConjugationAlexa Fluor® 647
ApplicationFlow Cyt
ClonalityMonoclonal
Clone Number24F.10C12
ImmunogenRecombinant Full Length Protein corresponding to Human PDCD1LG2.
PuritySize-exclusion chromatography
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.0975% Sodium azide Constituents: PBS
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Plays a critical role in induction and maintenance of immune tolerance to self (PubMed : 11224527, PubMed : 12538684). Acts as a ligand for the inhibitory receptor PDCD1/PD-1, inhibiting T-cell proliferation by blocking cell cycle progression and cytokine production (PubMed : 11224527). See full target information PDCD1LG2

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