Alexa Fluor® 647 Anti-beta 2 Microglobulin antibody [B2M01],Abcam,AB187602
Host
Mouse
Reactivity
Human
Application
ICC/IF, Flow Cyt
Conjugate
Alexa Fluor® 647
Platform ID
BAB743988445
Abcam
Contact
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Product Specifications
Scientific Background
Specifications
NameAlexa Fluor® 647 Anti-beta 2 Microglobulin antibody [B2M01]
Cat. No.AB187602
HostMouse
IsotypeIgG2a
ReactivityHuman
ConjugationAlexa Fluor® 647
ApplicationICC/IF, Flow Cyt
ClonalityMonoclonal
Clone NumberB2M01
Concentration1 mg/mL Batch dependent concentration
ImmunogenNative Full Length Protein corresponding to Human B2M.
PuritySize-exclusion chromatography
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.097% Sodium azide Constituents: PBS
Storage+4°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation (PubMed : 25356553). See full target information B2M
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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