Alexa Fluor 647 anti-IDO1 Antibody anti-IDO1 - 2E2/IDO1,BioLegend,654003

Clone 2E2/IDO1 reacts with mouse IDO1. It does not appear to react with mouse IDO2.Clone 2E2/IDO1 is the same clone as anti-IDO1 clone 2E2.6.

Host

Mouse

Reactivity

Mouse

Application

ICFC - Quality tested

Platform ID

BAB489833027

BioLegend

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Contact

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Product Specifications
Scientific Background

Specifications

NameAlexa Fluor 647 anti-IDO1 Antibody anti-IDO1 - 2E2/IDO1
Cat. No.654003
HostMouse
RRIDAB_2564584 (BioLegend Cat. No. 654003)AB_2564585 (BioLegend Cat. No. 654004)
IsotypeMouse IgG1, κ
ReactivityMouse
ApplicationICFC - Quality tested
ClonalityMonoclonal
Clone Number2E2/IDO1
Concentration0.5 mg/ml
TargetIDO1
ImmunogenRecombinant mouse IDO1.
PurityThe antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

IDO1 is also known as Indolamine 2,3-dioxygenase, Indole 2,3-dioxygenase, and Indoleamine-pyrrole 2,3-dioxygenase. IDO is a ubiquitously expressed cytoplasmic protein with a predicted molecular weight of approximately 45 kD. Indoleamine 2,3-dioxygenase (IDO) is one the best known IFN-γ inducible genes. The product of IDO gene catalyzes the degradation of the essential amino acid L-tryptophan to N-formylkynurenine. IDO has been implicated to protect against intracellular and extracellular pathogens. It also has been shown to maintain the special immune suppressive status of immune-privileged sites such as the brain, eyes, kidney, and placenta.

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