Alexa Fluor 647 anti-Tubulin beta 3 TUBB3 Antibody anti-beta 3 - TUJ1,BioLegend,801209
Additional reported applications (for the relevant formats) include: flow cytometry4, immunofluorescence microscopy1-5,7, immunohistochemistry5,7, and Western blotting8.This antibody is well characterized and highly reactive to neuron specific Class III ß-tubulin (ßIII). TUJ1 does not identify ß-tubulin found in glial cells. TUJ1 recognizes an epitope located within the last 15 C-terminal residues8.
Host
Mouse
Reactivity
Human, Mouse, Rat
Application
ICC - Quality testedICFC, 3D IHC, IHC-P - Verified
Platform ID
BAB909387866
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameAlexa Fluor 647 anti-Tubulin beta 3 TUBB3 Antibody anti-beta 3 - TUJ1
Cat. No.801209
HostMouse
RRIDAB_2686930 (BioLegend Cat. No. 801209)AB_2686931 (BioLegend Cat. No. 801210)
IsotypeMouse IgG2a, κ
ReactivityHuman, Mouse, Rat
ApplicationICC - Quality testedICFC, 3D IHC, IHC-P - Verified
ClonalityMonoclonal
Clone NumberTUJ1
Concentration0.5 mg/ml
TargetTubulin beta-3
ImmunogenThis antibody was raised against microtubules derived from rat brain.
PurityThe antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
Tubulin is the main component of microtubules. In adults, tubulin beta 3 (TUBB3) is primarily expressed in neurons and is commonly used as a neuronal marker. It plays an important role in neuronal cell proliferation and differentiation. Mutations in this gene cause congenital fibrosis of the type 3 extraocular muscles. Tubulin beta 3 (TUBB3) is also found in a wide range of tumors. Studies indicate that it is a predictive and prognostic marker in various tumors.
Category Paths
- Products>Primary Antibodies>IHC Antibodies
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