Alexa Fluor 647 anti-beta-Amyloid, 1-16 Antibody, beta-Amyloid, 1-16, 6E10,BioLegend,803021
This antibody is reactive to amino acid residue 1-16 of beta amyloid. The epitope lies within amino acids 3-8 of beta amyloid (EFRHDS).This antibody clone has been reported for use in immunohistochemistry of free-floating sections2,13.
Host
Mouse
Reactivity
Human
Application
IHC-P -Quality tested
Platform ID
BAB570505550
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameAlexa Fluor 647 anti-beta-Amyloid, 1-16 Antibody, beta-Amyloid, 1-16, 6E10
Cat. No.803021
HostMouse
RRIDAB_2783373 (BioLegend Cat. No. 803020)AB_2783374 (BioLegend Cat. No. 803021)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationIHC-P -Quality tested
ClonalityMonoclonal
Clone Number60000000000
Concentration0.5 mg/mL
Targetbeta-Amyloid 1-16
PurityThe antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
Alzheimer's disease is characterized by the accumulation of aggregated Aβ peptides in senile plaques and vascular deposits. Aβ peptides are derived from amyloid precursor proteins (APP) through sequential proteolytic cleavage of APP by β-secretases and γ-secretases generating diverse Aβ species. Aβ can aggregate to form soluble oligomeric species and insoluble fibrillar or amorphous assemblies. Some forms of the aggregated peptides are toxic to neurons.
Category Paths
- Products>Primary Antibodies>IHC Antibodies
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