Alexa Fluor® 647 anti-human CD285 (TLR5) Antibody, CD285, S16021I,BioLegend,394505
Host
Mouse
Reactivity
Human
Application
FC -Quality tested
Platform ID
BAB129915755
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameAlexa Fluor® 647 anti-human CD285 (TLR5) Antibody, CD285, S16021I
Cat. No.394505
HostMouse
RRIDAB_2820040 (BioLegend Cat. No. 394505)AB_2820041 (BioLegend Cat. No. 394506)
IsotypeMouse IgG2a, κ
ReactivityHuman
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone NumberS16021I
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD285
ImmunogenHuman TLR5 transfectants
PurityThe antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD285, also known as TLR5, is a 98 kD pattern recognition receptor that binds to bacterial flagellin. It is expressed on dendritic cells, classical monocytes and mucosal epithelial cells and is involved in activation of TLR5 induced NF-κB mediated activation of inflammatory-related target genes. Mutations in the TLR5 gene have been linked with susceptibility to systemic lupus erythematosus and Legionnaire’s disease.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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