Alexa Fluor® 647 anti-human CD371 (CLEC12A) Antibody, CD371, 50C1,BioLegend,353621

Host

Mouse

Reactivity

Human

Application

FC - Quality tested

Platform ID

BAB438346488

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NameAlexa Fluor® 647 anti-human CD371 (CLEC12A) Antibody, CD371, 50C1
Cat. No.353621
HostMouse
RRIDAB_2936772 (BioLegend Cat. No. 353621)AB_2936772 (BioLegend Cat. No. 353622)
IsotypeMouse IgG2a, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone Number50C1
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD371
Immunogen293T cells expressing CLEC12A-Flag
PurityThe antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD371 (CLEC12A), also known as DCAL-2, MICL or CLL-1, is a 30 kD type II transmembrane protein with extracellular C-type lectin domains, belonging to the C-type lectin family.  It is expressed on monocytes, granulocytes, NK cells, and basophils.  Its cytoplasmic ITIM motif modulates signaling cascades and is involved in phosphorylation of tyrosine residues in MAP kinases.

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