Alexa Fluor® 647 anti-human HLA-C antibody, HLA-C, DT-9,BioLegend,373308
Host
Mouse
Reactivity
Human
Application
FC - Quality tested
Platform ID
BAB281987783
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameAlexa Fluor® 647 anti-human HLA-C antibody, HLA-C, DT-9
Cat. No.373308
HostMouse
RRIDAB_2894582 (BioLegend Cat. No. 373307)AB_2894582 (BioLegend Cat. No. 373308)
IsotypeMouse IgG2b, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberDT-9
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetHLA-C
ImmunogenPurified tamarin MHC class I molecules, corresponding to human HLA-C
PurityThe antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
HLA-C belongs to the HLA class I heavy chain paralogues. MHC class I heavy chains associate with β2-microglobulin and are expressed on nearly all nucleated cells. MHC class I molecules are involved in the presentation of antigens to CD8+ T cells and thereby play an important role in cell-mediated immune responses and immune surveillance. Detailed characterization of the DT-9 clone indicates that it cross-reacts with HLA-E and certain HLA-A and HLA-B allotypes.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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