Alexa Fluor® 647 anti-human Podoplanin Antibody, Podoplanin, LpMab-21,BioLegend,395003

Host

Mouse

Reactivity

Human

Application

FC -Quality testedIHC-P -Verified

Platform ID

BAB620581502

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

BioLegend

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NameAlexa Fluor® 647 anti-human Podoplanin Antibody, Podoplanin, LpMab-21
Cat. No.395003
HostMouse
RRIDAB_2783309 (BioLegend Cat. No. 395003)AB_2783310 (BioLegend Cat. No. 395004)
IsotypeMouse IgG2a, κ
ReactivityHuman
ApplicationFC -Quality testedIHC-P -Verified
ClonalityMonoclonal
Clone NumberLpMab-21
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetPodoplanin
ImmunogenRecombinant human podoplanin
PurityThe antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

Podoplanin is a 40-43 kD type-I transmembrane sialomucin-type glycoprotein, also known as T1a, gp36, gp38, gp40, and Aggrus. Originally detected on the surface of podocytes, futher characterization showed podoplanin has a broad tissue distribution, including mesothelial cells, epithelial cells, follicular dendritic cells, and a variety of tumor cells. It has been reported that podoplanin is the ligand of CLEC2 and is involved in lymphatic vessel formation, platelet aggregation, and tumor metastasis. Podoplanin may serve as a useful marker for tumor diagnosis and prognosis.

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