Alexa Fluor 647 anti-mouse CD102 Antibody anti-CD102 - 3C4 (MIC2/4),BioLegend,105611
Additional reported applications (for the relevant formats) include: immunohistochemical staining2of acetone-fixed frozen sections,in vitroblocking of ligand binding1, and immunoprecipitation1. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 105608).
Host
Rat
Reactivity
Mouse
Application
FC -Quality tested
Platform ID
BAB557411838
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameAlexa Fluor 647 anti-mouse CD102 Antibody anti-CD102 - 3C4 (MIC2/4)
Cat. No.105611
HostRat
RRIDAB_2122183 (BioLegend Cat. No. 105611)AB_2122182 (BioLegend Cat. No. 105612)
IsotypeRat IgG2a, κ
ReactivityMouse
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone Number3C4 (MIC2/4)
Concentration0.5 mg/ml
TargetCD102
ImmunogenCOS cells transfected with mouse ICAM-2 cDNA
PurityThe antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD102 is a 55 kD immunoglobulin superfamily member, also known as ICAM-2. CD102 is a heavily glycosylated cell surface ligand for LFA-1 (CD11a/CD18). CD102 is constitutively expressed on vascular endothelial cells, some lymphocytes, monocytes, and platelets. CD102 is thought to be involved in lymphocyte recirculation and T cell activation. The 3C4(MIC2/4) antibody can block interactions between ICAM-2 and LFA-1.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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