Alexa Fluor® 647 anti-mouse CD170 (Siglec-F) Antibody, CD170, S17007L,BioLegend,155519
Host
Rat
Reactivity
Mouse
Application
FC - Quality tested
Platform ID
BAB505003213
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameAlexa Fluor® 647 anti-mouse CD170 (Siglec-F) Antibody, CD170, S17007L
Cat. No.155519
HostRat
RRIDAB_2890711 (BioLegend Cat. No. 155519)AB_2890711 (BioLegend Cat. No. 155520)
IsotypeRat IgG2a, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberS17007L
Concentration0.5 mg/mL
TargetCD170
PurityThe antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD170, also known as Siglec-F and Siglec-5, is a member of the sialic acid-binding immunoglobulin-like lectin (siglec) family of type I single pass transmembrane proteins. Siglec-F has four extracellular Ig-like domains and two cytoplasmic ITIM motifs and preferentially binds [alpha]-2,3-linked sialic acid. Siglec-F is expressed on eosinophils, alveolar macrophages and intestinal microfold (M) cells and induces apoptosis of lung eosinophils during allergic asthma.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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