Alexa Fluor 647 anti-mouse CD23 Antibody anti-CD23 - B3B4,BioLegend,101612
The B3B4 antibody is useful for blocking IgE activityin vivo. Additional reported applications (for the relevant formats) include: immunoprecipitation1, immunofluorescence microscopy,in vitroandin vivoblocking of ligand binding2-4, immunohistochemical staining of acetone-fixed frozen sections5, and spatial biology (IBEX)7,8.
Host
Rat
Reactivity
Mouse
Application
FC -Quality testedIHC-F -VerifiedSB -Reported in the literature, not verified in house
Platform ID
BAB269893591
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameAlexa Fluor 647 anti-mouse CD23 Antibody anti-CD23 - B3B4
Cat. No.101612
HostRat
RRIDAB_493479 (BioLegend Cat. No. 101611)AB_2103038 (BioLegend Cat. No. 101612)
IsotypeRat IgG2a, κ
ReactivityMouse
ApplicationFC -Quality testedIHC-F -VerifiedSB -Reported in the literature, not verified in house
ClonalityMonoclonal
Clone NumberB3B4
Concentration0.5 mg/ml
TargetCD23
ImmunogenComplex of IgE with Fcε receptor isolated from the mouse B hybridoma cell line O1.2B2
PurityThe antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD23 is a 45 kD protein also known as low affinity IgE Fc receptor, FcεRII, BLAST-2, Ly-42, or B6. It is a member of the Ig family, expressed on conventional B (but not B-1) cells and follicular dendritic cells. CD23 responds to high levels of IgE by downregulating IgE secretion.
Category Paths
- Products>Primary Antibodies>IHC Antibodies
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