Alexa Fluor® 647 anti-mouse CD3ε Antibody - CD3ε - 500A2,BioLegend,152320
Clone 500A2 antibody is able to partially cross-block the 17A2 and 145-2C11 antibodies, indicating that all three of these anti-CD3 antibodies recognize distinct but overlapping epitopes.
Host
Syrian Hamster
Reactivity
Mouse
Application
IHC-F - Quality testedFC - Verified
Platform ID
BAB500727795
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
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Product Specifications
Scientific Background
Specifications
NameAlexa Fluor® 647 anti-mouse CD3ε Antibody - CD3ε - 500A2
Cat. No.152320
HostSyrian Hamster
RRIDAB_2750182 (BioLegend Cat. No. 152320)
IsotypeSyrian Hamster IgG
ReactivityMouse
ApplicationIHC-F - Quality testedFC - Verified
ClonalityMonoclonal
Clone Number500A2
Concentration0.5 mg/mL
TargetCD3epsilon
ImmunogenMouse T cell receptor.
PurityThe antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.
Category Paths
- Products>Primary Antibodies>IHC Antibodies
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