Alexa Fluor® 647 anti-mouse CLEC4F Antibody, CLEC4F, 3E3F9,BioLegend,156803

Host

Mouse

Reactivity

Mouse, Rat

Application

IHC-F -Quality tested3D IHC -Verified

Platform ID

BAB433248936

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NameAlexa Fluor® 647 anti-mouse CLEC4F Antibody, CLEC4F, 3E3F9
Cat. No.156803
HostMouse
RRIDAB_2814081 (BioLegend Cat. No. 156803)AB_2814082 (BioLegend Cat. No. 156804)
IsotypeMouse IgG1, κ
ReactivityMouse, Rat
ApplicationIHC-F -Quality tested3D IHC -Verified
ClonalityMonoclonal
Clone Number3E3F9
Concentration0.5 mg/mL
TargetCLEC4F
PurityThe antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CLEC4F, also known as Kupffer cell receptor or KCR, is an 80 kDa type II transmembrane glycoprotein of the C-type lectin superfamily. It is expressed on resident Kupffer cells and infiltrating monocytes in the liver but not on macrophages in other tissues. CLEC4F interacts with alpha-galactosylceramide (α-GalCer) in a calcium-dependent manner and participates in the presentation of α-GalCer to natural killer T (NKT) cells.

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