Alexa Fluor® 647 anti-mouse Granzyme B Antibody, Granzyme B, S23006A,BioLegend,168805
Clones S23006A and GB11 partially block each other.
Host
Rat
Reactivity
Mouse
Application
ICFC - Quality tested
Platform ID
BAB699843438
BioLegend
Contact
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Product Specifications
Scientific Background
Specifications
NameAlexa Fluor® 647 anti-mouse Granzyme B Antibody, Granzyme B, S23006A
Cat. No.168805
HostRat
IsotypeRat IgG1, λ
ReactivityMouse
ApplicationICFC - Quality tested
ClonalityMonoclonal
Clone NumberS23006A
Concentration0.5 mg/mL
TargetGranzyme B
PurityThe antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
Granzyme B, also known as granzyme-2, serine protease B, CCP1, Asp-ase, and CTLA-1, is a 32 kD serine protease. Granzyme B is abundantly stored in the granules of cytotoxic T lymphocytes and NK cells. Low level of expression has been reported in granulocytes, B cells, and activated dendritic cells. Granzyme B is crucial for rapid induction of cell death and apoptosis through interaction with mannose-6-phosphate receptor.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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