Alexa Fluor 647 anti-mouse Ly-51 Antibody anti-Ly-51 - 6C3,BioLegend,108311

Additional reported applications (for the relevant formats) include: immunoprecipitation1,2and immunohistochemical staining3-5, 7-8of acetone-fixed frozen sections.

Host

Rat

Reactivity

Mouse

Application

FC -Quality tested

Platform ID

BAB132137217

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
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Product Specifications
Scientific Background

Specifications

NameAlexa Fluor 647 anti-mouse Ly-51 Antibody anti-Ly-51 - 6C3
Cat. No.108311
HostRat
RRIDAB_2099614 (BioLegend Cat. No. 108311)AB_2099613 (BioLegend Cat. No. 108312)
IsotypeRat IgG2a, κ
ReactivityMouse
ApplicationFC -Quality tested
ClonalityMonoclonal
Clone Number6C3
Concentration0.5 mg/ml
TargetLy-51
ImmunogenC57BL/6 mouse Pre-B lymphoma cell line (L1-2) plus Abelson murine leukemia virus-specific cytotoxic T-cell clones
PurityThe antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

Ly-51 is a 140 kD protein also known as 6C3/BP-1. It is a homodimeric cell-surface glycoprotein with aminopeptidase A (APA) activity. Ly-51 is expressed on B cell progenitors, bone marrow stromal cell lines, thymic dendritic cells, and cortical epithelial cells. Ly-51 expression can be upregulated by IL-7 stimulation.

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