Alexa Fluor 647 anti-rat CD11b/c Antibody anti-CD11b/c - OX-42,BioLegend,201814
Additional reported applications (for the relevant formats) include: immunohistochemistry of acetone-fixed frozen sections1,2, immunoprecipitation3,in vivoandin vitroblocking of C3bi binding3,4.
Host
Mouse
Reactivity
Rat
Application
FC -Quality testedIHC-F -Verified
Platform ID
BAB887998138
BioLegend
Contact
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Product Specifications
Scientific Background
Specifications
NameAlexa Fluor 647 anti-rat CD11b/c Antibody anti-CD11b/c - OX-42
Cat. No.201814
HostMouse
RRIDAB_2129391 (BioLegend Cat. No. 201814)
IsotypeMouse IgG2a, κ
ReactivityRat
ApplicationFC -Quality testedIHC-F -Verified
ClonalityMonoclonal
Clone NumberOX-42
Concentration0.5 mg/ml
TargetCD11b or CD11c
ImmunogenRat peritoneal macrophages.
PurityThe antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
The OX-42 antibody reacts with the CR3 complement (C3bi) receptor expressed on monocytes, granulocytes, macrophages, dendritic cells, and NK cells. This antibody appears to recognize a common epitope shared between CD11b and CD11c (integrin αMand αXchains). The OX-42 antibody precipitates three polypeptides with apparent molecular weights of 160, 103, and 95 kD, respectively. This antibody has been shown to block the formation of complement-mediated rosettes and leukocyte migration.
Category Paths
- Products>Primary Antibodies>IHC Antibodies
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