Alexa Fluor 700 anti-human CD41 Antibody anti-CD41 - HIP8,BioLegend,303728
Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections and blocking of platelet aggregation2. The HIP8 antibody has been reported to block the activation of platelets by various stimuli, including collagen, and ADP.
Host
Mouse
Reactivity
Human
Application
FC - Quality tested
Platform ID
BAB670768665
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameAlexa Fluor 700 anti-human CD41 Antibody anti-CD41 - HIP8
Cat. No.303728
HostMouse
RRIDAB_2566538 (BioLegend Cat. No. 303727)AB_2566539 (BioLegend Cat. No. 303728)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberHIP8
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD41
PurityThe antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 700 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD41 is a 125/25 kD α subunit of the gpIIb/IIIa (CD41/CD61) complex. CD41 is a heterodimer composed of a heavy chain (gpIIbα) and light chain (gpIIbβ) linked by a single disulfide bond. It is a member of the integrin family primarily expressed on platelets and megakaryocytes. CD41 has been reported to be involved with platelet aggregation and platelet attachment to the ECM. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor, and thrombin.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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