Alexa Fluor 700 anti-humanmouse Granzyme B Recombinant Antibody anti-Granzyme B - QA16A02,BioLegend,372221

Host

Mouse

Reactivity

Human, Mouse

Application

ICFC -Quality tested

Platform ID

BAB562087064

BioLegend

Headquarters

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Contact

Tel: 1-858-455-9588
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Product Specifications
Scientific Background

Specifications

NameAlexa Fluor 700 anti-humanmouse Granzyme B Recombinant Antibody anti-Granzyme B - QA16A02
Cat. No.372221
HostMouse
RRIDAB_2728388 (BioLegend Cat. No. 372221)AB_2728389 (BioLegend Cat. No. 372222)
IsotypeMouse IgG1, κ
ReactivityHuman, Mouse
ApplicationICFC -Quality tested
ClonalityRecombinant
Clone NumberQA16A02
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetGranzyme B
PurityThe antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 700 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

Granzyme B is a 32 kD serine protease, also known as granzyme-2, serine protease B, CCP1, Asp-ase, and CTLA-1. Granzyme B is abundantly stored in the granules of cytotoxic T lymphocytes and NK cells. Low level of expression has been reported in granulocytes, B cells, and activated dendritic cells. Granzyme B is crucial for rapid induction of cell death and apoptosis through interaction with mannose-6-phosphate receptor.

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