Alexa Fluor® 700 anti-mouse NK-1.1 Antibody, NK-1.1, S17016D,BioLegend,156511

Clone S17016D cross-blocks anti-mouse NK1.1 clone PK136, and can stain for NK1.1 post-formaldehyde and methanol-based fixation based on in-house testing.

Host

Mouse

Reactivity

Mouse

Application

FC - Quality tested

Platform ID

BAB068633920

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

BioLegend

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NameAlexa Fluor® 700 anti-mouse NK-1.1 Antibody, NK-1.1, S17016D
Cat. No.156511
HostMouse
RRIDAB_2892322 (BioLegend Cat. No. 156511)AB_2892322 (BioLegend Cat. No. 156512)
IsotypeMouse IgG2a, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberS17016D
Concentration0.5 mg/mL
TargetNK-1.1
ImmunogenMouse NK1.1-transfectants
PurityThe antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 700 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cellsin vitroand rejection of bone marrow allograftsin vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.