Alpha-1 Antitrypsin (SERPINA1) Rabbit mAb,ABclonal,A21972

Reactivity

Human

Application

WB, IF/ICC, ELISA

Conjugate

Unconjugated

Platform ID

BAB105416256

ABclonal

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500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

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Product Specifications
Scientific Background
Synonyms

Specifications

NameAlpha-1 Antitrypsin (SERPINA1) Rabbit mAb
Cat. No.A21972
Accession NumberP01009
Gene ID (Entrez)5265
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB, IF/ICC, ELISA
Working DilutionsWB:30000 - 120000 | IF/ICC:1:50 - 1:200 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC54184
Molecular Weight62 kDa/55 kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a serine protease inhibitor belonging to the serpin superfamily whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. This protein is produced in the liver, the bone marrow, by lymphocytic and monocytic cells in lymphoid tissue, and by the Paneth cells of the gut. Defects in this gene are associated with chronic obstructive pulmonary disease, emphysema, and chronic liver disease. Several transcript variants encoding the same protein have been found for this gene.

Synonyms

PI; A1A; AAT; PI1; A1AT; nNIF; PRO2275; alpha1AT; Alpha-1 Antitrypsin (SERPINA1)

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