Angiogenin antibody [MANG-1],Genetex,GTX42776

Host

Mouse

Reactivity

Human

Application

IHC-P IHC-Fr ELISA

Conjugate

Unconjugated

Platform ID

BAB529447796

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameAngiogenin antibody [MANG-1]
Cat. No.GTX42776
Gene ID (Entrez)283
HostMouse
IsotypeIgM
ReactivityHuman
ConjugationUnconjugated
ApplicationIHC-P IHC-Fr ELISA
ClonalityMonoclonal
Concentration0.3 mg/ml (Please refer to the vial label for the specific concentration.)
TargetANG
ImmunogenRecombinant human angiogenin
PurityTissue Culture Supernatant
Appearance/FormLiquid
FormulationPBS, 1% BSA,0.01% Thimerosal
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is an exceedingly potent mediator of new blood vessel formation. It hydrolyzes cellular tRNAs resulting in decreased protein synthesis and is similar to pancreatic ribonuclease. In addition, the mature peptide has antimicrobial activity against some bacteria and fungi, including S. pneumoniae and C. albicans. Alternative splicing results in two transcript variants encoding the same protein. This gene and the gene that encodes ribonuclease, RNase A family, 4 share promoters and 5' exons. Each gene splices to a unique downstream exon that contains its complete coding region. [provided by RefSeq, Aug 2014]

Synonyms

angiogenin , ALS9 , HEL168 , RAA1 , RNASE4 , RNASE5

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