Angiostatin antibody [6F34],Genetex,GTX52545

Host

Mouse

Reactivity

Human

Application

WB

Conjugate

Unconjugated

Platform ID

BAB933921142

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameAngiostatin antibody [6F34]
Cat. No.GTX52545
Gene ID (Entrez)5340
HostMouse
IsotypeIgG2
ReactivityHuman
ConjugationUnconjugated
ApplicationWB
ClonalityMonoclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
TargetPLG
ImmunogenHuman recombinant Angiostatin Kringle 1 - 3
PurityProtein G purifiedFrom tissue culture supernatant
Appearance/FormLiquid
FormulationPBS,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009]

Synonyms

PLG , plasminogen , Plasminogen , Angiostatin , Plasmin

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