Anti-14-3-3 gamma/YWHAG antibody [EPR9654(B)] - BSA and Azide free,Abcam,AB248786

What is this antibody validated in? Anti-14-3-3 gamma/YWHAG antibody [EPR9654(B)] - BSA and Azide free (ab248786) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB) in Human samples. What is the molecular weight of 14-3-3 gamma/YWHAG? Anti-14-3-3 gamma/YWHAG [EPR9654(B)] - BSA and Azide free (ab248786) specifically detects a band for 14-3-3 gamma/YWHAG (UniProt: P61981) at a molecular weight of 28kDa. Specificity confirmed The specificity of Anti-14-3-3 gamma/YWHAG antibody [EPR9654(B)] - BSA and Azide free (ab248786) has been confirmed by Western blot testing in YWHAG Knockout HEK293T cell line, ab266734 . Other related products We have a range of other formats of antibody clone [EPR9654(B)] also available for your convenience: ab137048 , Carrier free - ab248786 Conjugation ready Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications. Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold. Compatibility This product is compatible with the Maxpar ® Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar ® is a trademark of Fluidigm Canada Inc.

Host

Rabbit

Reactivity

Human

Application

WB

Platform ID

BAB703507885

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-14-3-3 gamma/YWHAG antibody [EPR9654(B)] - BSA and Azide free
Cat. No.AB248786
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationWB
ClonalityMonoclonal
Clone NumberEPR9654(B)
Concentration1.002 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Constituents: PBS
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways (PubMed : 15696159, PubMed : 16511572, PubMed : 36732624). Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif (PubMed : 15696159, PubMed : 16511572, PubMed : 36732624). Binding generally results in the modulation of the activity of the binding partner (PubMed : 16511572). Promotes inactivation of WDR24 component of the GATOR2 complex by binding to phosphorylated WDR24 (PubMed : 36732624). Participates in the positive regulation of NMDA glutamate receptor activity by promoting the L-glutamate secretion through interaction with BEST1 (PubMed : 29121962). Reduces keratinocyte intercellular adhesion, via interacting with PKP1 and sequestering it in the cytoplasm, thereby reducing its incorporation into desmosomes (PubMed : 29678907). See full target information YWHAG

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