Anti-68kDa Neurofilament/NF-L antibody,Abcam,AB24520

To raise this antibody bovine intermediate filaments were prepared from spinal cords by the method of Delacourte et al. and the cytoskeletal material was dissolved in 6M urea. To ensure greater specificity for NFL, animals were boosted with recombinant mouse NFL purified from bacteria. This antibody was generated in chicken by standard procedures and immunoglobulin was extracted from egg yolk. This is the chicken homologue of mammalian IgG and can be used in the same general way, with the caveat that this type of antibody does not bind either Protein A or Protein G.

Host

Chicken

Reactivity

Mouse, Rat, Cow

Application

WB, IHC

Platform ID

BAB642226050

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-68kDa Neurofilament/NF-L antibody
Cat. No.AB24520
HostChicken
IsotypeIgY
ReactivityMouse, Rat, Cow
ApplicationWB, IHC
ClonalityPolyclonal
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.065% Sodium azide Constituents: PBS
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Neurofilaments usually contain three intermediate filament proteins : NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks (By similarity). See full target information NEFL

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