Anti-ABCA1 antibody [AB.H10],Abcam,AB18180

What is this antibody validated in? Anti-ABCA1 antibody [AB.H10] (ab18180) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Flow Cyt), Immunohistochemistry (IHC-P) in Human, Mouse samples. What is the molecular weight of ABCA1? Anti-ABCA1 [AB.H10] (ab18180) specifically detects a band for ABCA1 (UniProt: O95477) at a molecular weight of 254kDa. Trusted by the scientific community Anti-ABCA1 [AB.H10] (ab18180) was first used in a scientific publication in 2005 and has been cited over 200 times in peer-reviewed journals. Reviewed by scientists Anti-ABCA1 [AB.H10] (ab18180) has over 15 independent reviews from customers. Specificity confirmed The specificity of Anti-ABCA1 antibody [AB.H10] (ab18180) has been confirmed by Western blot testing in ABCA1 Knockout Mouse liver samples.

Host

Mouse

Reactivity

Mouse, Human

Application

WB, Flow Cyt, IHC-P

Platform ID

BAB893050654

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-ABCA1 antibody [AB.H10]
Cat. No.AB18180
HostMouse
IsotypeIgG1
ReactivityMouse, Human
ApplicationWB, Flow Cyt, IHC-P
ClonalityMonoclonal
Clone NumberAB.H10
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human ABCA1 aa 1800 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.05% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Catalyzes the translocation of specific phospholipids from the cytoplasmic to the extracellular/lumenal leaflet of membrane coupled to the hydrolysis of ATP (PubMed : 24097981, PubMed : 35974019). Thereby, participates in phospholipid transfer to apolipoproteins to form nascent high density lipoproteins/HDLs (PubMed : 14754908). Transports preferentially phosphatidylcholine over phosphatidylserine (PubMed : 24097981). May play a similar role in the efflux of intracellular cholesterol to apolipoproteins and the formation of nascent high density lipoproteins/HDLs (PubMed : 10533863, PubMed : 14754908, PubMed : 24097981, PubMed : 35974019). Translocates phospholipids from the outer face of the plasma membrane and forces it through its gateway and annulus into an elongated hydrophobic tunnel in its extracellular domain (PubMed : 35974019). See full target information ABCA1

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.