Anti-ABCG1 antibody [EP1366Y],Abcam,AB52617

What is this antibody validated in? Anti-ABCG1 antibody [EP1366Y] (ab52617) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunocytochemistry/immunofluorescence (ICC/IF) in Cow, Human, Mouse, Rat samples. What is the molecular weight of ABCG1? Anti-ABCG1 [EP1366Y] (ab52617) specifically detects a band for ABCG1 (UniProt: P45844) at a molecular weight of 75kDa. Trusted by the scientific community Anti-ABCG1 [EP1366Y] (ab52617) was first used in a scientific publication in 2007 and has been cited over 80 times in peer-reviewed journals. Reviewed by scientists Anti-ABCG1 [EP1366Y] (ab52617) has over 5 independent reviews from customers. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Other related products We have a range of other formats of antibody clone [EP1366Y] also available for your convenience: ab52617, HRP - ab201776 , Carrier free - ab218528 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Mouse, Rat, Cow, Human

Application

WB, ICC/IF

Platform ID

BAB955931721

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-ABCG1 antibody [EP1366Y]
Cat. No.AB52617
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Cow, Human
ApplicationWB, ICC/IF
ClonalityMonoclonal
Clone NumberEP1366Y
Concentration0.25 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Catalyzes the efflux of phospholipids such as sphingomyelin, cholesterol and its oxygenated derivatives like 7beta-hydroxycholesterol and this transport is coupled to hydrolysis of ATP (PubMed : 17408620, PubMed : 24576892). The lipid efflux is ALB-dependent (PubMed : 16702602). Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages. Prevents cell death by transporting cytotoxic 7beta-hydroxycholesterol (PubMed : 17408620). See full target information ABCG1

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