Anti-ABHD14B antibody [011] - BSA and Azide free,Abcam,AB276068

Host

Rabbit

Reactivity

Human

Application

IP, WB

Platform ID

BAB830969203

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-ABHD14B antibody [011] - BSA and Azide free
Cat. No.AB276068
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationIP, WB
ClonalityMonoclonal
Clone Number011
ImmunogenRecombinant Fragment Protein within Human ABHD14B aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationConstituents: PBS
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Acts as an atypical protein-lysine deacetylase in vitro (PubMed : 31478652). Catalyzes the deacetylation of lysine residues using CoA as substrate, generating acetyl-CoA and the free amine of protein-lysine residues (PubMed : 31478652). Additional experiments are however required to confirm the protein-lysine deacetylase activity in vivo (Probable). Has hydrolase activity towards various surrogate p-nitrophenyl (pNp) substrates, such as pNp-butyrate, pNp-acetate and pNp-octanoate in vitro, with a strong preference for pNp-acetate (PubMed : 14672934, PubMed : 31478652). May activate transcription (PubMed : 14672934). See full target information ABHD14B

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