Anti-ADAMTS1 antibody [OTI1B4],Abcam,AB236497

Clone OTI1B4 (formerly 1B4).

Host

Mouse

Reactivity

Human

Application

WB

Platform ID

BAB333418027

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-ADAMTS1 antibody [OTI1B4]
Cat. No.AB236497
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationWB
ClonalityMonoclonal
Clone NumberOTI1B4
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human ADAMTS1 aa 400-650. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.3 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Cleaves aggrecan, a cartilage proteoglycan, at the '1938-Glu-|-Leu-1939' site (within the chondroitin sulfate attachment domain), and may be involved in its turnover (By similarity). Has angiogenic inhibitor activity. Active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia. May play a critical role in follicular rupture. See full target information ADAMTS1

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