Anti-AICDA antibody [mAID-2],Abcam,AB169522
Host
Rat
Reactivity
Human
Application
IHC-P
Platform ID
BAB148073242
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Product Specifications
Scientific Background
Specifications
NameAnti-AICDA antibody [mAID-2]
Cat. No.AB169522
HostRat
IsotypeIgG2a
ReactivityHuman
ApplicationIHC-P
ClonalityMonoclonal
Clone NumbermAID-2
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Mouse Aicda conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.09% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation (SHM), gene conversion, and class-switch recombination (CSR) in B-lymphocytes by deaminating C to U during transcription of Ig-variable (V) and Ig-switch (S) region DNA. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation. See full target information Aicda
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
Request a product
Please provide the required information below so that we can quickly source your products.