Anti-AIMP2/p38 antibody,Abcam,AB67471
Host
Mouse
Reactivity
Human
Application
WB
Platform ID
BAB273235664
Abcam
Contact
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Product Specifications
Scientific Background
Specifications
NameAnti-AIMP2/p38 antibody
Cat. No.AB67471
HostMouse
IsotypeIgG
ReactivityHuman
ApplicationWB
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Human AIMP2.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Required for assembly and stability of the aminoacyl-tRNA synthase complex (PubMed : 19131329). Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor. See full target information AIMP2
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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