Anti-AP3 antibody,Abcam,AB85075

Host

Rabbit

Reactivity

Human

Application

WB

Platform ID

BAB954421182

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-AP3 antibody
Cat. No.AB85075
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationWB
ClonalityPolyclonal
ImmunogenSynthetic Peptide within Human AP3D1. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLyophilized
ShippingBlue Ice
FormulationPreservative: 0.02% Sodium azide
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Involved in process of CD8+ T-cell and NK cell degranulation (PubMed : 26744459). In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals (By similarity). See full target information AP3D1

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