Anti-AQP-10 antibody - C-terminal,Abcam,AB182794

Target data Aquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and water transport across the plasma membrane along their osmotic gradient (PubMed : 11573934, PubMed : 12084581, PubMed : 21733844, PubMed : 23382902, PubMed : 30420639). Could also be permeable to urea (PubMed : 12084581). Among aquaglyceroporins, it exhibits a unique pH-gated glycerol transport activity, being more active at acidic pH. It most likely plays a central role in the efflux of glycerol formed during triglyceride hydrolysis in adipocytes and in glycerol uptake by enterocytes, as both processes occur and are stimulated at acidic pH (PubMed : 11573934, PubMed : 23382902, PubMed : 30420639). See full target information AQP10