Anti-ARL13B antibody [N295B/66],Abcam,AB136648

What is this antibody validated in? Anti-ARL13B antibody [N295B/66] (ab136648) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P) in Mouse, Rat samples. What is the molecular weight of ARL13B? Anti-ARL13B [N295B/66] (ab136648) specifically detects a band for ARL13B (UniProt: Q3SXY8) at a molecular weight of 60kDa. Trusted by the scientific community Anti-ARL13B [N295B/66] (ab136648) was first used in a scientific publication in 2012 and has been cited over 30 times in peer-reviewed journals. Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact [email protected]

Host

Mouse

Reactivity

Mouse, Rat

Application

WB, IHC-P

Platform ID

BAB027997113

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-ARL13B antibody [N295B/66]
Cat. No.AB136648
HostMouse
IsotypeIgG2a
ReactivityMouse, Rat
ApplicationWB, IHC-P
ClonalityMonoclonal
Clone NumberN295B/66
Concentration1 mg/mL Batch dependent concentration
PurityAffinity purification
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 6.97% L-Arginine
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze fit; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development : required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic interneurons in the developing cerebral cortex. Plays a role in ciliar trafficking of phosphatidylinositol phosphatase INPP5E in ciliogenesis (PubMed : 38219074). May regulate ARF6- and RAB22A-dependent endocytic recycling traffic (PubMed : 23223633). See full target information ARL13B

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