Anti-ATF1 (phospho S63) antibody,Abcam,AB226812

Host

Rabbit

Reactivity

Mouse, Human

Application

WB

Platform ID

BAB967514894

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-ATF1 (phospho S63) antibody
Cat. No.AB226812
HostRabbit
IsotypeIgG
ReactivityMouse, Human
ApplicationWB
ClonalityPolyclonal
Concentration0.94 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human Cyclic AMP-dependent transcription factor ATF-1 phospho S63. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.025% Proclin 300 Constituents: PBS, 20% Glycerol (glycerin, glycerine), 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data This protein binds the cAMP response element (CRE) (consensus : 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation. See full target information Cyclic AMP-dependent transcription factor ATF-1 phospho S63

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