Anti-ATF3 antibody [5A9B9],Abcam,AB233797

Host

Mouse

Reactivity

Human

Application

Flow Cyt, WB

Platform ID

BAB155158575

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-ATF3 antibody [5A9B9]
Cat. No.AB233797
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationFlow Cyt, WB
ClonalityMonoclonal
Clone Number5A9B9
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Human ATF3.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.05% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data This protein binds the cAMP response element (CRE) (consensus : 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter.. Isoform 2. Activates transcription presumably by sequestering inhibitory cofactors away from the promoters.. Isoform 3. Stress-induced isoform, counteracts the transcriptional repression of isoform 1. See full target information ATF3

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