Anti-ATG7 antibody,Abcam,AB99001

Host

Rabbit

Reactivity

Arabidopsis thaliana

Application

WB

Platform ID

BAB718089618

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-ATG7 antibody
Cat. No.AB99001
HostRabbit
IsotypeIgG
ReactivityArabidopsis thaliana
ApplicationWB
ClonalityPolyclonal
ImmunogenFull Length Protein corresponding to Arabidopsis thaliana ATG7. The exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationConstituents: Whole serum
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes. Involved in the senescence process (PubMed : 12070171). Involved in the degradation of damaged peroxisomes (PubMed : 24368788). Involved in the non-selective degradation of chlorophylls and photosynthetic proteins during stress-induced leaf yellowing (PubMed : 24510943). See full target information ATG7

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