Anti-ATG9A antibody [EPR2450(2)],Abcam,AB108338
What is this antibody validated in? Anti-ATG9A antibody [EPR2450(2)] (ab108338) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples. What is the molecular weight of ATG9A? Anti-ATG9A [EPR2450(2)] (ab108338) specifically detects a band for ATG9A (UniProt: Q7Z3C6) at a molecular weight of 94kDa. Trusted by the scientific community Anti-ATG9A [EPR2450(2)] (ab108338) was first used in a scientific publication in 2011 and has been cited over 80 times in peer-reviewed journals. Reviewed by scientists Anti-ATG9A [EPR2450(2)] (ab108338) has over 10 independent reviews from customers. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Specificity confirmed The specificity of Anti-ATG9A antibody [EPR2450(2)] (ab108338) has been confirmed by Western blot testing in ATG9A Knockout HAP1 cells. Other related products We have a range of other formats of antibody clone [EPR2450(2)] also available for your convenience: ab108338, Alexa Fluor® 488 - ab206252 , Alexa Fluor® 647 - ab206253 , Carrier free - ab223528 , ab309518 , Carrier free - ab309519 , APC - ab310808 , PE - ab310890 , Alexa Fluor® 594 - ab311672 , Alexa Fluor® 568 - ab312947 , Alexa Fluor® 750 - ab320894 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rabbit
Reactivity
Mouse, Rat, Human
Application
ICC/IF, WB, Flow Cyt (Intra), IP, IHC-P
Platform ID
BAB530645841
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Phospholipid scramblase involved in autophagy by mediating autophagosomal membrane expansion (PubMed : 22456507, PubMed : 27510922, PubMed : 29437695, PubMed : 32513819, PubMed : 32610138, PubMed : 33106659, PubMed : 33468622, PubMed : 33850023). Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome (PubMed : 16940348, PubMed : 22456507, PubMed : 33106659). Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 (ATG2A or ATG2B) from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion (PubMed : 33106659). Also required to supply phosphatidylinositol 4-phosphate to the autophagosome initiation site by recruiting the phosphatidylinositol 4-kinase beta (PI4KB) in a process dependent on ARFIP2, but not ARFIP1 (PubMed : 30917996). In addition to autophagy, also plays a role in necrotic cell death (By similarity). See full target information ATG9A
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