Anti-Adiponectin antibody [19F1],Abcam,AB22554

What is this antibody validated in? Anti-Adiponectin antibody [19F1] (ab22554) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P) in Human, Mouse samples. What is the molecular weight of Adiponectin? Anti-Adiponectin [19F1] (ab22554) specifically detects a band for Adiponectin (UniProt: Q15848) at a molecular weight of 26kDa. Trusted by the scientific community Anti-Adiponectin [19F1] (ab22554) was first used in a scientific publication in 2005 and has been cited over 100 times in peer-reviewed journals. Reviewed by scientists Anti-Adiponectin [19F1] (ab22554) has over 15 independent reviews from customers.

Host

Mouse

Reactivity

Mouse, Human

Application

ICC, IHC-P, WB

Platform ID

BAB646623938

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Adiponectin antibody [19F1]
Cat. No.AB22554
HostMouse
IsotypeIgG
ReactivityMouse, Human
ApplicationICC, IHC-P, WB
ClonalityMonoclonal
Clone Number19F1
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Human ADIPOQ.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.05% Sodium azide Constituents: PBS, 0.1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW. See full target information ADIPOQ

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